Running a Python Masonite application in aaPanel Running a Python Masonite application in aaPanel involves installing the Python manager, setting up a virtual environment, installing dependencies, and configuring a WSGI server (like Gunicorn) behind Nginx. Use the "Python Project" management feature in aaPanel to handle the environment, dependencies, and reverse proxy configuration seamlessly.   Step-by-Step Deployment Guide Install Python Manager: Log in to aaPanel. Go to  Software Store , find  Python Project Manager , and install it. Upload Project Files: Use the aaPanel  File Manager  to upload your Masonite project files to a directory (e.g.,  /www/wwwroot/masonite-app ). Configure Project in Python Manager: Open  Python Project Manager . Click  Add Project . Project Name:  Enter a name. Path:  Select the folder where you uploaded the Masonite app. Python Version:  Select Python 3.8+ (recommended for Masonite). Framework:  Choose "Masonite" (or "Flask/WSGI" if Masonite isn't listed, as it's WSGI compatible). Startup File/Script:  Point to  wsgi.py  (usually  app/wsgi.py  or similar). Port:  Set a port (e.g., 8000). Select "Install Dependencies"  to install from  requirements.txt . Ensure  Binding Domain  is filled to map your domain to the app. Configure Environment Variables & Database: In the project settings in the Python Manager, ensure the  .env  file is configured correctly for your database (MySQL/PostgreSQL) and that the  APP_URL  matches your domain. Run Migrations & Start: Use the terminal in aaPanel or the command line in the project manager to run Masonite commands: bash craft migrate Restart the application in the Python Manager to apply changes. Setup Nginx Reverse Proxy: The Python Manager should automatically create an Nginx configuration that proxies requests from port 80/443 to your Python app port (e.g., 8000).   If the app fails to start, check the logs in the Python Project Manager to resolve dependency or environment issues